Evolved Peptide Therapeutics
From target to therapeutic candidate. AI-guided peptide evolution plus modular bioconjugation for next-generation biologics.
Peptide Evolution
Evolve peptides for any target receptor. Our platform searches billions of sequence variants, applying evolutionary pressure for binding, selectivity, and stability simultaneously. Get optimized binders ready for conjugation.
- Target receptor analysis & binding site mapping
- AI-guided evolution across billion+ sequence space
- Multi-objective selection (affinity + selectivity + stability)
- Iterative optimization with assay feedback integration
- Full lineage tracking & variant comparison
- Synthesis-ready sequences with detailed annotations
Scaffold Conjugation
Connect your evolved peptides to validated scaffolds with known pharmacokinetic profiles. Site-specific conjugation preserves peptide activity while providing predictable half-life and distribution.
- Validated carrier proteins with characterized PK
- Site-specific conjugation chemistry
- Activity preservation optimization
- Stability & aggregation assessment
- Linker selection & optimization
- Analytics support for DAR confirmation
Multi-Agonist Design
Build single molecules that target 2-3 pathways simultaneously. Combine evolved peptides on a common scaffold for synergistic pharmacology—dual agonists, antagonist combinations, or mixed-mode therapeutics.
- Multi-target strategy design
- Peptide compatibility assessment
- Stoichiometry optimization
- Synergy modeling & prediction
- Complex conjugate synthesis support
- Functional activity profiling
Lead Optimization
Refine existing peptides or conjugates based on experimental feedback. Our platform integrates assay data to guide the next evolution cycle, continuously improving your candidates toward clinical goals.
- Baseline characterization & liability profiling
- Assay data integration & feedback loops
- Property-guided evolution campaigns
- Selectivity enhancement
- Developability optimization
- Lineage analysis & decision support