The Protein Evolution Foundry
We don't predict what proteins might do. We evolve proteins that perform—building the next generation of peptide therapeutics through AI-guided directed evolution.
Beyond Prediction
The biologics industry has embraced AI for structure prediction, but prediction alone doesn't create therapeutics. Fabricagen takes the next step: using AI to guide actual molecular evolution.
Our platform doesn't just predict what might bind—it evolves peptides through billions of variants, selecting for binding, selectivity, and stability simultaneously. Then we conjugate the winners to proven scaffolds with fixed pharmacokinetic profiles.
The result: modular therapeutics where you can tune the pharmacodynamics without reformulating the delivery. Dual agonists. Tri-peptide conjugates. Multi-target molecules from mix-and-match components.
Evolution, Not Prediction
AI-guided directed evolution at scale
The Modular Therapeutics Thesis
What if you could build therapeutics like software—with standardized components that snap together?
Evolved Peptides
AI-guided evolution finds optimal binders for any target
Fixed PK Scaffolds
Validated carriers with predictable half-life profiles
Modular Assembly
Mix and match PD modules on standardized PK platforms
How We Work
Principles that guide our approach to therapeutic development.
Biology First
We let biology guide our algorithms. Real assay feedback drives evolutionary pressure, not just computational metrics.
Modular Design
Fixed pharmacokinetics with interchangeable pharmacodynamics. Build therapeutic cocktails from proven components.
Partnership Model
We work closely with pharma and biotech partners to co-develop next-generation peptide therapeutics.
Fabricagen, Inc.
Superior, CO